Despite incompatible Blood Group, Mother donates kidney to give new lease of life to ailing son

Pune: A mother in the mid fifties donated her kidney to give a new lease of life to her ailing son. The transplant was carried out at Noble Hospital, Pune by a team of doctors on 11 June 2025. The 31 year old recipient from Bangladesh and his mother are now fine and ready to go home.  

Giving details about the case , Dr.Avinash Ignatius, Consultant Nephrologist and Transplant Physician at Noble Hospitals and Research Centre said that the patient was suffering  IgA nephropathy, also known as Berger’s disease and was diagnosed after a biopsy was conducted. IgA nephropathy is a rare kidney disease that occurs when the body’s immune system produces an abnormal type of immunoglobulin A (IgA) antibodies that cause inflammation in the kidneys. This damages the small filters that remove waste and fluid from the blood. Over time, the inflammation can make it harder for the kidneys to filter waste, potentially leading to kidney damage or failure.

The patient was on dialysis. Both the kidneys of the patient were damaged and transplant was necessary to save his life. Only his mother was available for donation in his family, However her blood group was AB + ve, but the patient’s blood group was B+ve. He would have ideally required a donor with B or O group.
So in such cases there is a high risk that the recipients ‘ body will reject the kidney. So the recipient was tested for antibodies and special injections were given to prevent production of the antibodies. In addition a process called plasmapheresis was carried out to filter out existing antibodies from the blood. Rejection and risk of infection due to higher immunosuppression was the major risk in this procedure and requires special care in the pre and post transplant period. The transplant was successful and the creatine level of the patient has come to normal.

The patient will have to take care for a few months before getting back to routine work.

The transplant team consisted of Nephrologists Dr.Avinash Ignatius and  Dr. Rakesh Shinde , Transplant Surgeons Dr.Vikram Satav  and Dr Shashikant Bhange, Dr.Shardul Date (Vascular Surgeon) and Anaesthetist team of  Dr Sangeeta Chandrashekhar and Dr Nilesh Wasmatkar and Intensivist Dr.BD Bande.

Dr.Divij Mane, Director Noble Hospitals said that the case demonstrates the expertise and skills of our team in handling such complicated cases. With top experts , state of the art facilities and world class JCI accredited procedures, we ensure that the patient gets the best possible treatment for good outcomes .

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